Sonographic measurement of the thymus in infants
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Sonographic measurement of the thymus in infants. / Hasselbalch, H.; Nielsen, M. B.; Jeppesen, D.; Pedersen, J. F.; Karkov, J.
I: European Radiology, Bind 6, Nr. 5, 1996, s. 700-703.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Sonographic measurement of the thymus in infants
AU - Hasselbalch, H.
AU - Nielsen, M. B.
AU - Jeppesen, D.
AU - Pedersen, J. F.
AU - Karkov, J.
PY - 1996
Y1 - 1996
N2 - A new method of measuring the size of the thymus in infants less than 1 year of age is presented. The width of the thymus was measured in a transverse image while the area of the largest lobe was assessed in a longitudinal image. The thymic index was then defined as the product of these two values. Intra-and interobserver variation analysis were performed in 23 infants. Each infant was scanned alternately by both of two radiologists, and later the same day the measurements were repeated. The mean differences between the first and second measurements (intraobserver variation) were -0.25 (2 SD 7.56) and -1.13 (2 SD 10.80), respectively, for the two observers. The mean difference between the first measurements of the two observers (interobserver variation) was 1.47 (2 SD 9.39). In a postmortem study of 12 infants the thymic index measured by sonography showed an acceptable correlation to the actual volume (c = 0.80) and weight (c = 0.87) of the thymus. In conclusion, our sonographic estimate of the volume of the thymus, the thymic index, in infants under 8 months of age seems to be easy, reliable and reproducible.
AB - A new method of measuring the size of the thymus in infants less than 1 year of age is presented. The width of the thymus was measured in a transverse image while the area of the largest lobe was assessed in a longitudinal image. The thymic index was then defined as the product of these two values. Intra-and interobserver variation analysis were performed in 23 infants. Each infant was scanned alternately by both of two radiologists, and later the same day the measurements were repeated. The mean differences between the first and second measurements (intraobserver variation) were -0.25 (2 SD 7.56) and -1.13 (2 SD 10.80), respectively, for the two observers. The mean difference between the first measurements of the two observers (interobserver variation) was 1.47 (2 SD 9.39). In a postmortem study of 12 infants the thymic index measured by sonography showed an acceptable correlation to the actual volume (c = 0.80) and weight (c = 0.87) of the thymus. In conclusion, our sonographic estimate of the volume of the thymus, the thymic index, in infants under 8 months of age seems to be easy, reliable and reproducible.
KW - Infant
KW - Thymus gland
KW - Ultrasonography
UR - http://www.scopus.com/inward/record.url?scp=0030345376&partnerID=8YFLogxK
U2 - 10.1007/BF00187675
DO - 10.1007/BF00187675
M3 - Journal article
C2 - 8934137
AN - SCOPUS:0030345376
VL - 6
SP - 700
EP - 703
JO - European Radiology
JF - European Radiology
SN - 0938-7994
IS - 5
ER -
ID: 331495847