A prospective study of PET/CT in initial staging of small-cell lung cancer: comparison with CT, bone scintigraphy and bone marrow analysis

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Standard

A prospective study of PET/CT in initial staging of small-cell lung cancer : comparison with CT, bone scintigraphy and bone marrow analysis. / Fischer, B M; Mortensen, J; Langer, S W; Loft, A; Berthelsen, A K; Petersen, B I; Daugaard, G; Lassen, U; Hansen, H H.

I: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Bind 18, Nr. 2, 02.2007, s. 338-45.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Fischer, BM, Mortensen, J, Langer, SW, Loft, A, Berthelsen, AK, Petersen, BI, Daugaard, G, Lassen, U & Hansen, HH 2007, 'A prospective study of PET/CT in initial staging of small-cell lung cancer: comparison with CT, bone scintigraphy and bone marrow analysis', Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, bind 18, nr. 2, s. 338-45. https://doi.org/10.1093/annonc/mdl374

APA

Fischer, B. M., Mortensen, J., Langer, S. W., Loft, A., Berthelsen, A. K., Petersen, B. I., Daugaard, G., Lassen, U., & Hansen, H. H. (2007). A prospective study of PET/CT in initial staging of small-cell lung cancer: comparison with CT, bone scintigraphy and bone marrow analysis. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, 18(2), 338-45. https://doi.org/10.1093/annonc/mdl374

Vancouver

Fischer BM, Mortensen J, Langer SW, Loft A, Berthelsen AK, Petersen BI o.a. A prospective study of PET/CT in initial staging of small-cell lung cancer: comparison with CT, bone scintigraphy and bone marrow analysis. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2007 feb.;18(2):338-45. https://doi.org/10.1093/annonc/mdl374

Author

Fischer, B M ; Mortensen, J ; Langer, S W ; Loft, A ; Berthelsen, A K ; Petersen, B I ; Daugaard, G ; Lassen, U ; Hansen, H H. / A prospective study of PET/CT in initial staging of small-cell lung cancer : comparison with CT, bone scintigraphy and bone marrow analysis. I: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2007 ; Bind 18, Nr. 2. s. 338-45.

Bibtex

@article{b0c6aefacd8d428c91a75610f23768b0,
title = "A prospective study of PET/CT in initial staging of small-cell lung cancer: comparison with CT, bone scintigraphy and bone marrow analysis",
abstract = "BACKGROUND: Small-cell lung cancer (SCLC) accounts for 15%-20% of all lung cancer cases. Accurate and fast staging is mandatory when choosing treatment, but current staging procedures are time consuming and lack sensitivity.PATIENTS AND METHODS: A prospective study was designed to examine the role of combined positron emission tomography/computed tomography (PET/CT) compared with standard staging (CT, bone scintigraphy and immunocytochemical assessment of bone marrow biopsy) of patients with SCLC. Thirty-four consecutive patients were included. Twenty-nine patients received initial PET/CT.RESULTS: PET/CT caused change of stage in 5/29 (17%). Excluding patients with unconfirmed findings or pleural effusion, the sensitivity for accurate staging of patients with extensive disease was the following: for standard staging 79%, PET 93% and PET/CT 93%. Specificity was 100%, 83% and 100%, respectively.CONCLUSION: The results from this first study on PET/CT in SCLC indicates that PET/CT can simplify and perhaps even improve the accuracy of the current staging procedure in SCLC. A larger clinical trial, preferably with consequent histological confirmation in case of discordance, however, is warranted.",
keywords = "Aged, Bone Marrow, Bone Neoplasms, Carcinoma, Small Cell, Female, Fluorodeoxyglucose F18, Humans, Lung Neoplasms, Male, Middle Aged, Neoplasm Staging, Positron-Emission Tomography, Prospective Studies, Radiopharmaceuticals, Sensitivity and Specificity, Tomography, X-Ray Computed, Comparative Study, Journal Article",
author = "Fischer, {B M} and J Mortensen and Langer, {S W} and A Loft and Berthelsen, {A K} and Petersen, {B I} and G Daugaard and U Lassen and Hansen, {H H}",
year = "2007",
month = feb,
doi = "10.1093/annonc/mdl374",
language = "English",
volume = "18",
pages = "338--45",
journal = "Annals of Oncology",
issn = "0923-7534",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - A prospective study of PET/CT in initial staging of small-cell lung cancer

T2 - comparison with CT, bone scintigraphy and bone marrow analysis

AU - Fischer, B M

AU - Mortensen, J

AU - Langer, S W

AU - Loft, A

AU - Berthelsen, A K

AU - Petersen, B I

AU - Daugaard, G

AU - Lassen, U

AU - Hansen, H H

PY - 2007/2

Y1 - 2007/2

N2 - BACKGROUND: Small-cell lung cancer (SCLC) accounts for 15%-20% of all lung cancer cases. Accurate and fast staging is mandatory when choosing treatment, but current staging procedures are time consuming and lack sensitivity.PATIENTS AND METHODS: A prospective study was designed to examine the role of combined positron emission tomography/computed tomography (PET/CT) compared with standard staging (CT, bone scintigraphy and immunocytochemical assessment of bone marrow biopsy) of patients with SCLC. Thirty-four consecutive patients were included. Twenty-nine patients received initial PET/CT.RESULTS: PET/CT caused change of stage in 5/29 (17%). Excluding patients with unconfirmed findings or pleural effusion, the sensitivity for accurate staging of patients with extensive disease was the following: for standard staging 79%, PET 93% and PET/CT 93%. Specificity was 100%, 83% and 100%, respectively.CONCLUSION: The results from this first study on PET/CT in SCLC indicates that PET/CT can simplify and perhaps even improve the accuracy of the current staging procedure in SCLC. A larger clinical trial, preferably with consequent histological confirmation in case of discordance, however, is warranted.

AB - BACKGROUND: Small-cell lung cancer (SCLC) accounts for 15%-20% of all lung cancer cases. Accurate and fast staging is mandatory when choosing treatment, but current staging procedures are time consuming and lack sensitivity.PATIENTS AND METHODS: A prospective study was designed to examine the role of combined positron emission tomography/computed tomography (PET/CT) compared with standard staging (CT, bone scintigraphy and immunocytochemical assessment of bone marrow biopsy) of patients with SCLC. Thirty-four consecutive patients were included. Twenty-nine patients received initial PET/CT.RESULTS: PET/CT caused change of stage in 5/29 (17%). Excluding patients with unconfirmed findings or pleural effusion, the sensitivity for accurate staging of patients with extensive disease was the following: for standard staging 79%, PET 93% and PET/CT 93%. Specificity was 100%, 83% and 100%, respectively.CONCLUSION: The results from this first study on PET/CT in SCLC indicates that PET/CT can simplify and perhaps even improve the accuracy of the current staging procedure in SCLC. A larger clinical trial, preferably with consequent histological confirmation in case of discordance, however, is warranted.

KW - Aged

KW - Bone Marrow

KW - Bone Neoplasms

KW - Carcinoma, Small Cell

KW - Female

KW - Fluorodeoxyglucose F18

KW - Humans

KW - Lung Neoplasms

KW - Male

KW - Middle Aged

KW - Neoplasm Staging

KW - Positron-Emission Tomography

KW - Prospective Studies

KW - Radiopharmaceuticals

KW - Sensitivity and Specificity

KW - Tomography, X-Ray Computed

KW - Comparative Study

KW - Journal Article

U2 - 10.1093/annonc/mdl374

DO - 10.1093/annonc/mdl374

M3 - Journal article

C2 - 17060487

VL - 18

SP - 338

EP - 345

JO - Annals of Oncology

JF - Annals of Oncology

SN - 0923-7534

IS - 2

ER -

ID: 167431633