This two-part case collection presents the profiles of 39 family-run firms that are 'Hénokiens', a French association whose members have survived for more than two centuries. The oldest member, a hostel in Japan named Hoshi Ryokan, has been in business for 1,300 years over 46 generations. The family business narrative is based on five analytical pillars: family assets, roadblocks, succession planning, professionalization and innovation. Instructors can take a single profile of a member firm and use it to illustrate one or more of the five themes. The cases highlight the key people and events that have marked economic history over the centuries, making for a fascinating read as well as offering an alternative business model of leadership and longevity.